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Clonidine is a modern, highly effective drug, which has a sedative and hypotensive action. The result of the drug use is the expansion of the brain vessels and lowering blood pressure. This medicine may also be used as a single agent to reduce intraocular pressure in open-angle glaucoma. Therapeutic effect lasts for about 6-12 hours.

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Branded names of Clonidine

There are many drugs, in which the main active ingredient is Clonidine. Their principle of action is similar to drug with a brand name of Clonidine, but European and American pharmaceutical companies have registered it under a different trade name. The drug belongs to a group of hypertensive and vascular stabilizers. Vessels of the brain become wider and the blood flow are increased, and as a result, blood pressure decreases.

In Germany, the brand name of Clonidine is presented by drug of Catapres, in Canada − Arkamin. The main active substance is hydrochloride of clonidine. Catapres comes in tablet form or transdermal patches. It has hypotensive and sedative effects.

In the UK, the brand name of Clonidine is used in drugs such as Dixarit and Duraclon. Besides the basic functional purpose it is used at strong oncologic pain, when treatment of opiates does not give the desired effect.

Also the brand name of Clonidine can be buy Clonidine or used in medications which are sold under new names such as Apo-Clonidine, Novo-Clonidine, Nu-Clonidine. The principle of action of these drugs is no different from that of the main and has the same pharmacological properties. All the above mentioned medications are available in assortment of our pharmacy.

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Clonidine impact on the body occurs at the level of neurohumoral regulation of vascular tone. After passing through the blood-brain barrier (BBB) Clonidine is selectively activated in the α2-adrenergic receptors of the center of the medulla oblongata. Due to this, the sympathetic impulsation from the central nervous system (CNS) are inhibited, lumen of the blood vessels increases and blood pressure is lowered.

At treatment of this drug particular attention should be paid to the control of blood pressure. Sudden failure of the drug changes the heart rate and can cause a hypertensive crisis, limb tremors, irritability, headache, and nausea. This is the famous “withdrawal syndrome of the drug.” If within the first two days positive influence of Clonidine on the patient organism is not observed, the treatment is stopped.

It is undesirable to take the drug when your work requires concentration and attention span. Speed of psychomotor and physical reactions depends on the influence of Clonidine on the human body. During treatment with this drug, alcohol intake is absolutely excluded.

Due to its central action, somatic vegetative symptoms of opiate and alcohol withdrawal are eliminated. There is an analgesic and sedative Clonidine influence on the body. A feeling of fear goes away and symptoms of cardiovascular and other disorders gradually decrease. Proper use of Clonidine can help you quickly and effectively deal with illness.

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Clonidine − a modern drug of centrally acting

Effective therapeutic agent is used for systemic application at arterial hypertension and hypertensive crisis. This medication may also be used as a mototherapy to reduce intraocular pressure at open-angle glaucoma.

The dosage of Сlonidine 0.1 mg is prescribed by a doctor individually. However, the initial dose is not more than 75 mg three times a day. Typically, the concentration of the used drug is gradually increased to 900 mg. The course of treatment with Clonidine 0.1 mg on the average makes two months.

The therapeutic effect of this unique drug lasts from six to twelve hours. During this period, renal blood flow and vessels tonus of the brain are increased several times. Thus, Clonidine 0.1 mg has a sedative effect on the patient organism. Therefore this drug should not be use by drivers, as this medicinal product may cause a drowsiness and fatigue.

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Description of the drug Clonidine

Clonidine is a medication of central action, designed to treat high blood pressure (hypertension) and migraine. By stimulating alpha-receptors in the brain Clonidine reduces vascular resistance.

The drug Clonidine is also used for treatment of acute myocardial infarction (if there are no signs of cardiogenic shock), headache of vascular origin, pheochromocytoma, dysmenorrhea and menopause (treatment of vasomotor symptoms), syndrome of Gilles de la Tourette and nicotine dependence.

Action of the drug Clonidine is accompanied by the expansion of peripheral blood vessels all over the organism. The drug increases renal blood flow, at the same time improving the tone of cerebral blood vessels and reducing cerebral blood flow, and has a strong sedative and analgesic effect.

At intake Clonidine orally, it is well absorbed. The half-life of Clonidine is about 12-16 hours, the duration of therapeutic action from 2 to 24 hours. At taking the drug Clonidine orally, about 60% of the drug is excreted by the kidneys, mainly as metabolites.

Hypotensive impact of Clonidine is accompanied by a decrease in cardiac output that reduces peripheral vascular resistance, including blood vessels of the kidneys. The drug Clonidine also reduces the intraocular pressure by decreasing secretion and improving the outflow of aqueous humor.

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Make purchases on the Internet is as easy and safe as in an ordinary shop, but much more convenient. When you buy Clonidine online, you get a number of advantages. You can place your order Clonidine online, without leaving the house at any time of day. You do not need to waste your strength on the tedious goings to the drugstores of the city in search of the drug Clonidine.

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The older people become, the more often they are faced with the problem of high arterial pressure and related ailments. Clonidine ‒ is an effective antihypertensive medication, which is taken orally for the regulation of vascular tone. This medication is used to lower pressure, including intraocular pressure at glaucoma.

Get a prescription on Clonidine from the attending specialist is not always obtained. Typically, this is due to the fact that pharmaceutical products on the basis of Clonidine ‒ are the medications of strict record-keeping, and as a result, doctors are very reluctant to prescribe them for prescriptions while the patients are forced to look for alternative treatment options.

Our online drugstore allows you to buy the drug Clonidine without showing a medical prescription to pharmacist.

Clonidine is produced as a white crystalline powder that is readily soluble in water but poorly soluble in chloroform, ether and alcohol. At intake orally, it is well absorbed from the gastrointestinal tract. The dosage of the drug Clonidine is determined individually.

Avoid concurrent use with:

  • Hormonal contraceptives (may increase the sedative action);
  • Tricyclic antidepressants (decrease antihypertensive action);
  • Verapamil (possibility of development of heart block);
  • Prazosin (possibility of changing the antihypertensive action);
  • Propranolol (development of an additive antihypertensive effect, sedative action, dry mouth);
  • Cyclosporine.

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Contraindications to the usage of Clonidine

Clonidine is contraindicated at hypersensitivity to any drug component, cardiogenic shock, arterial hypotension, obliterating diseases of peripheral arteries, AV block II-III degree, sick sinus syndrome, depression.

The usage of Clonidine drug is absolutely contraindicated during pregnancy and breastfeeding period. Also, the drug should not be used by patients that have such diagnoses as atherosclerosis of the arteries of the brain, severe heart failure, and alcoholism. It is undesirable the usage of the drug Clonidine after recent myocardial infarction as well as at chronic renal failure.

At sharp cancellation of this drug it may be observed a so-called “ricochet syndrome”, which is accompanied by a sharp increase of arterial pressure. To avoid this effect, the dosage of Clonidine should be gradually reduced.

During the treatment period is often not recommended to engage in activities that may be potentially dangerous, requiring speed of psychomotor reactions and high levels of concentration.

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